[6] Santos Laguna 2-0 Tigres UANL [5] 2021-01-18 01:06
Stadium: Estadio TSM Corona Round: 2
Referee: Fernando Guerrero Ramirez Home Manager: Guillermo Almada Away Manager: Ricardo Ferretti
Head to Head
| Mexic - Liga MX | 2020/09/13 00:00 | Tigres UANL v Santos Laguna | L | 2-0 |
| Mexic - Liga MX | 2020/02/17 00:45 | Santos Laguna v Tigres UANL | W | 2-1 |
| Mexic - Liga MX | 2019/10/06 00:00 | Tigres UANL v Santos Laguna | L | 4-0 |
| CONCACAF Champions Cup | 2019/04/11 00:00 | Santos Laguna v Tigres UANL | W | 3-2 |
| CONCACAF Champions Cup | 2019/04/04 02:00 | Tigres UANL v Santos Laguna | L | 3-0 |
| Mexic - Liga MX | 2019/02/03 01:00 | Tigres UANL v Santos Laguna | L | 2-1 |
| Mexic - Liga MX | 2018/08/19 23:00 | Santos Laguna v Tigres UANL | W | 3-1 |
| Mexic - Champion of Champions | 2018/07/16 01:00 | Tigres UANL v Santos Laguna | L | 4-0 |
| Mexic - Liga MX | 2018/05/06 23:00 | Santos Laguna v Tigres UANL | W | 2-0 |
| Mexic - Liga MX | 2018/05/04 00:30 | Tigres UANL v Santos Laguna | L | 2-0 |
| Mexic - Liga MX | 2018/01/14 01:00 | Tigres UANL v Santos Laguna | L | 2-1 |
| Mexic - Liga MX | 2017/07/30 23:30 | Santos Laguna v Tigres UANL | D | 1-1 |
| Mexic - Liga MX | 2017/01/08 01:00 | Tigres UANL v Santos Laguna | D | 0-0 |
| Mexic - Liga MX | 2016/07/17 23:00 | Santos Laguna v Tigres UANL | D | 0-0 |
| Mexic - Liga MX | 2016/04/24 00:00 | Santos Laguna v Tigres UANL | W | 2-1 |
| Mexic - Liga MX | 2015/11/01 01:00 | Tigres UANL v Santos Laguna | D | 2-2 |
| Mexic - Liga MX | 2015/05/17 00:00 | Tigres UANL v Santos Laguna | W | 0-1 |
| Mexic - Liga MX | 2015/05/14 00:00 | Santos Laguna v Tigres UANL | D | 1-1 |
| Mexic - Liga MX | 2015/03/21 03:30 | Santos Laguna v Tigres UANL | D | 2-2 |
| Mexic - Cupa | 2014/10/30 03:00 | Tigres UANL v Santos Laguna | W | 2-4 |
| Mexic - Liga MX | 2014/10/01 02:00 | Tigres UANL v Santos Laguna | D | 1-1 |
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