| Columbia - Liga Regionala | 2022/05/17 13:00 | Envigado FC - Rezerve v FC Leones - Rezerve | L | 4-0 |
| Columbia - Liga Regionala | 2022/10/31 14:00 | FC Leones - Rezerve v Universidad de Antioquia | D | 2-2 |
| Columbia - Liga Regionala | 2022/10/03 15:02 | Club Deportivo La Chalaca v FC Leones - Rezerve | W | 1-3 |
| Columbia - Liga Regionala | 2022/09/24 21:27 | FC Leones - Rezerve v E.D.P IND. Medellin | L | 0-2 |
| Columbia - Liga Regionala | 2022/09/21 17:00 | Sol de Oriente v FC Leones - Rezerve | L | 1-0 |
| Columbia - Liga Regionala | 2022/09/05 15:34 | FC Leones - Rezerve v Talento y Vida | L | 2-3 |
| Columbia - Liga Regionala | 2022/08/30 15:00 | Medellin City FC v FC Leones - Rezerve | L | 4-0 |
| Columbia - Liga Regionala | 2022/08/16 15:11 | FC Leones - Rezerve v Lula FC | L | 2-7 |
| Columbia - Liga Regionala | 2022/07/26 15:30 | FC Leones - Rezerve v Club Deportivo La Chalaca | L | 3-4 |
| Columbia - Liga Regionala | 2022/11/25 17:00 | Atletico Nacional Medellin - Rezerve v Envigado FC - Rezerve | L | 3-1 |
| Columbia - Liga Regionala | 2022/11/22 17:00 | Real Santuario v Envigado FC - Rezerve | W | 0-2 |
| Columbia - Liga Regionala | 2022/11/15 17:00 | Envigado FC - Rezerve v CD Gallegol | D | 1-1 |
| Columbia - Liga Regionala | 2022/10/31 15:00 | Talento y Vida v Envigado FC - Rezerve | W | 0-1 |
| Columbia - Liga Regionala | 2022/10/18 13:00 | Medellin City FC v Envigado FC - Rezerve | L | 1-0 |
| Columbia - Liga Regionala | 2022/10/11 17:00 | Envigado FC - Rezerve v Molino Viejo | L | 0-2 |
| Columbia - Liga Regionala | 2022/10/04 16:43 | Total Soccer FC v Envigado FC - Rezerve | W | 1-3 |
| Columbia - Liga Regionala | 2022/07/27 13:13 | Envigado FC - Rezerve v Sellos Colombianos | W | 3-2 |