Stadium: Duane Stadium Round: 1
Home Manager: Dan Curran Away Manager: Chris Villarrial
| NCAAF | 2021/11/13 17:00 | Merrimack v St.Francis (PA) | W | 6-22 |
| NCAAF | 2019/09/14 16:00 | St.Francis (PA) v Merrimack | W | 42-14 |
| NCAAF | 2022/11/12 17:00 | Duquesne v St.Francis (PA) | W | 14-51 |
| NCAAF | 2022/11/05 16:30 | St.Francis (PA) v Georgetown | W | 38-24 |
| NCAAF | 2022/10/29 16:00 | St.Francis (PA) v Sacred Heart | W | 44-14 |
| NCAAF | 2022/10/22 17:00 | Stonehill v St.Francis (PA) | W | 13-17 |
| NCAAF | 2022/10/15 17:00 | St.Francis (PA) v LIU Brooklyn | W | 57-7 |
| NCAAF | 2022/10/01 16:00 | Central Connecticut v St.Francis (PA) | W | 13-39 |
| NCAAF | 2022/09/24 18:00 | St.Francis (PA) v Norfolk State | W | 45-26 |
| NCAAF | 2022/09/17 20:00 | St.Francis (PA) v Wagner | W | 27-7 |
| NCAAF | 2022/11/12 17:00 | Merrimack v Central Connecticut | W | 20-14 |
| NCAAF | 2022/10/29 17:00 | Merrimack v Stonehill | W | 17-10 |
| NCAAF | 2022/10/22 17:00 | Sacred Heart v Merrimack | W | 25-31 |
| NCAAF | 2022/10/15 17:00 | Wagner v Merrimack | W | 17-54 |
| NCAAF | 2022/10/08 17:00 | Merrimack v Duquesne | W | 28-21 |
| NCAAF | 2022/10/01 17:00 | LIU Brooklyn v Merrimack | W | 23-24 |
| NCAAF | 2022/09/24 18:00 | Merrimack v Delaware State | W | 26-13 |
| NCAAF | 2022/09/16 23:00 | Merrimack v Harvard | L | 21-28 |