Head to Head
| NCAAF | 2009/10/31 12:00 | Houston v Southern Mississippi | L | 50-43 |
| NCAAF | 2006/12/01 12:00 | Houston v Southern Mississippi | L | 34-20 |
| NCAAF | 2006/10/14 12:00 | Southern Mississippi v Houston | W | 31-27 |
| NCAAF | 2005/11/13 12:00 | Houston v Southern Mississippi | L | 27-24 |
| NCAAF | 2004/10/07 12:00 | Southern Mississippi v Houston | W | 35-29 |
| NCAAF | 2003/11/08 12:00 | Houston v Southern Mississippi | W | 10-31 |
| NCAAF | 2001/10/27 12:00 | Southern Mississippi v Houston | W | 58-14 |
| NCAAF | 2000/10/28 12:00 | Houston v Southern Mississippi | W | 3-6 |
Home History
| NCAAF | 2010/11/13 12:00 | Central Florida v Southern Mississippi | W | 21-31 |
| NCAAF | 2010/11/06 12:00 | Tulane v Southern Mississippi | W | 30-46 |
| NCAAF | 2010/10/30 12:00 | Southern Mississippi v UAB | L | 49-50 |
| NCAAF | 2010/10/16 12:00 | Memphis v Southern Mississippi | W | 19-41 |
| NCAAF | 2010/10/09 12:00 | Southern Mississippi v East Carolina | L | 43-44 |
| NCAAF | 2010/10/02 12:00 | Southern Mississippi v Marshall | W | 41-16 |
| NCAAF | 2010/09/25 12:00 | Louisiana Tech v Southern Mississippi | W | 12-13 |
| NCAAF | 2010/09/17 12:00 | Southern Mississippi v Kansas | W | 31-16 |
Away History
| NCAAF | 2010/11/13 12:00 | Houston v Tulsa | L | 25-28 |
| NCAAF | 2010/11/05 12:00 | Houston v Central Florida | L | 33-40 |
| NCAAF | 2010/10/30 12:00 | Memphis v Houston | W | 17-56 |
| NCAAF | 2010/10/23 12:00 | SMU v Houston | W | 20-45 |
| NCAAF | 2010/10/16 12:00 | Rice v Houston | L | 34-31 |
| NCAAF | 2010/10/09 12:00 | Houston v Mississippi State | L | 24-47 |
| NCAAF | 2010/09/25 12:00 | Houston v Tulane | W | 42-23 |
| NCAAF | 2010/09/18 12:00 | UCLA v Houston | L | 31-13 |
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