[8] Liverpool 3-1 Southampton [18] 2022-11-12 15:00
Stadium: Anfield Round: 16
Referee: Simon Hooper Home Manager: Jurgen Klopp Away Manager: Ralph Hasenhuttl
Head to Head
| Anglia - Premier League | 2022/05/17 18:45 | Southampton v Liverpool | W | 1-2 |
| Anglia - Premier League | 2021/11/27 15:00 | Liverpool v Southampton | W | 4-0 |
| Anglia - Premier League | 2021/05/08 19:15 | Liverpool v Southampton | W | 2-0 |
| Anglia - Premier League | 2021/01/04 20:00 | Southampton v Liverpool | L | 1-0 |
| Anglia - Premier League | 2020/02/01 15:00 | Liverpool v Southampton | W | 4-0 |
| Anglia - Premier League | 2019/08/17 14:00 | Southampton v Liverpool | W | 1-2 |
| Anglia - Premier League | 2019/04/05 19:00 | Southampton v Liverpool | W | 1-3 |
| Anglia - Premier League | 2018/09/22 14:00 | Liverpool v Southampton | W | 3-0 |
Home History
| Anglia - Cupa EFL | 2022/11/09 20:00 | Liverpool v Derby | W | 3-2 |
| Anglia - Premier League | 2022/11/06 16:30 | Tottenham v Liverpool | W | 1-2 |
| Liga Campionilor UEFA | 2022/11/01 20:00 | Liverpool v Napoli | W | 2-0 |
| Anglia - Premier League | 2022/10/29 18:45 | Liverpool v Leeds | L | 1-2 |
| Liga Campionilor UEFA | 2022/10/26 19:00 | Ajax v Liverpool | W | 0-3 |
| Anglia - Premier League | 2022/10/22 11:30 | Nottm Forest v Liverpool | L | 1-0 |
| Anglia - Premier League | 2022/10/19 18:30 | Liverpool v West Ham | W | 1-0 |
| Anglia - Premier League | 2022/10/16 15:30 | Liverpool v Man City | W | 1-0 |
Away History
| Anglia - Cupa EFL | 2022/11/09 19:45 | Southampton v Sheff Wed | W | 7-6 |
| Anglia - Premier League | 2022/11/06 14:00 | Southampton v Newcastle | L | 1-4 |
| Anglia - Premier League | 2022/10/29 14:00 | Crystal Palace v Southampton | L | 1-0 |
| Anglia - Premier League | 2022/10/23 13:00 | Southampton v Arsenal | D | 1-1 |
| Anglia - Premier League | 2022/10/19 18:30 | Bournemouth v Southampton | W | 0-1 |
| Anglia - Premier League | 2022/10/16 13:00 | Southampton v West Ham | D | 1-1 |
| Anglia - Premier League | 2022/10/08 14:00 | Man City v Southampton | L | 4-0 |
| Anglia - Premier League | 2022/10/01 14:00 | Southampton v Everton | L | 1-2 |
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